In vitro release profiles for INTAC® single entity, FDCs, and multi-modal preparations1-3

INTAC® can be tailored to a variety of release profiles from minutes up to 24 hours


1. Bartholomäus J, Schwier S, Brett M, Stahlberg HJ, Galia E, Strothmann K. New abuse deterrent formulation (ADF) technology for immediate-release opioids. Drug Dev Deliv. 2013;13(8):76-81.
2. Wening K, Barnscheid L. Abuse deterrent formulations for fixed-dose combinations and products with multi-modal release properties for opioids and stimulants using INTAC® technology. Poster presented at: AAPS Annual Meeting 2015; Orlando, FL.
3.Wening K, Schwier S, Stahlberg HJ, Galia E. Application of hot-melt extrusion technology in immediate-release abuse-deterrent formulations. November 2017, Journal of opioid management 13(6):473-484